Determination of the test substance concentration in dosing formulations required in GLP studies is conducted using HPLC, GC, LC-MS/MS, and spectrophotometer, etc. In addition, analytical method validation is conducted prior to determination to assure the reliability of the analytical method.

Determination of the test substance concentration in the dietary formulations required in GLP studies is conducted by HPLC, GC, LC-MS/MS, and spectrophotometer, etc. In addition, analytical method validation is conducted prior to determination to assure the reliability of the analytical method.

We are able to conduct carcinogenicity studies in rodents by oral and dermal administration. We have extensive background data and can perform characterization tests combining "properties," "IR spectra," and "purity or content" as standard items to confirm characteristics and stability of the test substance required in the GLP studies. In addition, analytical method validation is conducted prior to quantitative analysis to assure the reliability of the analytical method.
Test items of the characterization study are listed below.

Method development (dosing formulation analysis, dietary formulation analysis, trace analysis of the formulation, etc.) is conducted to establish optimum analytical methods based on advanced analysis techniques. Atypical methods are also welcome. Please do not hesitate to consult us about the above and other analysis techniques.